Professor Andrew Boyle is a cardiologist who studies left ventricular remodeling, the process by which the heart weakens and becomes ineffective following heart attacks and with advancing age. In particular, his research focuses on the molecular and cellular mechanisms of fibrosis and stem cell function in the heart.
Andrew received his medical degree from Monash University and then completed cardiology advanced training in Melbourne. It was during this time he noticed that early treatments for heart attack were very successful at keeping patients alive, but the late heart failure that ensued was difficult to treat. He became interested in the emerging research field of stem cell therapy for heart disease, with a view to regenerating the damaged heart muscle that occurred during a heart attack. He undertook a PhD at the University of Melbourne studying cardiac regeneration, and then moved to the US and continued this study as a fellow at Johns Hopkins University. He then joined the faculty at the University of California San Francisco, becoming Associate Professor of Medicine, where his laboratory focused on the effects of ageing on left ventricular remodeling, funded by the US National Institutes of Health.
After 7 years there, he moved to the University of Newcastle and the Hunter Medical Research Institute (HMRI) where he now continues this research. Andrew has a research laboratory based at HMRI where he studies pre-clinical models of left ventricular remodeling, and he also performs clinical research at the John Hunter Hospital.
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